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KMID : 1044320180200010041
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Annals of Clinical Neurophysiology
2018 Volume.20 No. 1 p.41 ~ p.43
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Intermediate syndrome after dermal exposure to organophosphate insecticide
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Lee Su-Bin
Ryu Seung-Ho
Park Doo-Yong
Park Jong-Ho
Kim Jee-Young
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Abstract
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Intermediate syndrome (IMS) typically occurs at 24?96 hours following organophosphate (OP) poisoning, after an acute cholinergic crisis, but before OP-induced delayed polyneuropathy. It is characterized by proximal muscle weakness and respiratory insufficiency, which is a major contributing factor of OP-related morbidity and mortality. We report an atypical IMS case showing rapid-onset ascending paralysis and respiratory disturbance with an acute cholinergic crisis occurring 4?5 days after skin exposure to OP.
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KEYWORD
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Organophosphate poisoning, Respiratory insufficiency, Cholinergic
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